Abstract
Tumor cells suffer a metabolic reprogramming which allows them to use metabolic fuels (glucose, glutamine, lipids) throughanabolic fates to support their enhanced proliferation and other carcinogenesis-related features. The present review tries to address andsummarize the broad and growing information available about this reprogramming, whose pieces, put together, make up a complexscheme that encompasses different complexity scales, from cells to systemic networks.
Keywords: Aerobic glycolysis, cancer metabolism, glutaminolysis, metabolic reprogramming, tumor microenvironment.
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Current Pharmaceutical Design
Title:Glutamine, Glucose and other Fuels for Cancer
Volume: 20 Issue: 15
Author(s): Maria Victoria Ruiz-Perez, Francisca Sanchez-Jimenez, Francisco J. Alonso, Juan A. Segura, Javier Marquez and Miguel Angel Medina
Affiliation:
Keywords: Aerobic glycolysis, cancer metabolism, glutaminolysis, metabolic reprogramming, tumor microenvironment.
Abstract: Tumor cells suffer a metabolic reprogramming which allows them to use metabolic fuels (glucose, glutamine, lipids) throughanabolic fates to support their enhanced proliferation and other carcinogenesis-related features. The present review tries to address andsummarize the broad and growing information available about this reprogramming, whose pieces, put together, make up a complexscheme that encompasses different complexity scales, from cells to systemic networks.
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Ruiz-Perez Victoria Maria, Sanchez-Jimenez Francisca, Alonso J. Francisco, Segura A. Juan, Marquez Javier and Medina Angel Miguel, Glutamine, Glucose and other Fuels for Cancer, Current Pharmaceutical Design 2014; 20 (15) . https://dx.doi.org/10.2174/13816128113199990482
| DOI https://dx.doi.org/10.2174/13816128113199990482 | Print ISSN 1381-6128 |
| Publisher Name Bentham Science Publisher | Online ISSN 1873-4286 |
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